Virus-associated nucleases: evidence for endonuclease and exonuclease activity in rabbitpox and vaccinia viruses.
نویسندگان
چکیده
The endonucleolytic action of a deoxyribonuclease activity in rabbitpox and vaccinia virus was established by change in sedimentation rate of denatured (3)H-lambda deoxyribonucleic acid substrate. The presence of two deoxyribonuclease activities in pox-virus is confirmed. Exo- and endonuclease activities are unmasked by treatment of purified virus with the detergent Nonidet P-40 and further enhanced by treatment of viral "cores" with trypsin.
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ورودعنوان ژورنال:
- Journal of virology
دوره 9 3 شماره
صفحات -
تاریخ انتشار 1972